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Compute reverse complement of the nucleotide sequence

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Sequence:

• Both DNA and RNA sequence is converted into reverse-complementing sequence of DNA.
• IUPAC ambiguity codes of the two possible nucleotides are converted as following: R↔Y, K↔M, S and W unchanged.
• Ambiguity codes of the three possible nucleotides are converted as following: B↔V, D↔H.
• Upper and lower case is preserved and can be used to mark regions of interest.
• All other symbols, including spaces and new line feeds, are left unchanged.
• FASTA header, if detected, is preserved.
• Multiple sequences with FASTA headers are complemented individually with headers preserved.
• Browser computes reverse complement without sending your sequence to the server.